Canada in Science - January 2025

Muscle-derived myostatin is a major endocrine driver of follicle-stimulating hormone synthesis

Journal Issue: Science. 2025 Jan 17;387(6731):329-336..

Authors: Ongaro L, Zhou X, Wang Y, Schultz H, Zhou Z, Buddle ERS, Brûlé E, Lin YF, Schang G, Hagg A, Castonguay R, Liu Y, Su GH, Seidah NG, Ray KC, Karp SJ, Boehm U, Ruf-Zamojski F, Sealfon SC, Walton KL, Lee SJ, Bernard DJ.

PubMed ID: 39818879

Daniel Bernard Lab

β-Glucan reprograms neutrophils to promote disease tolerance against influenza A virus

Journal Issue: Nat Immunol. 2025 Feb;26(2):174-187.

Authors: Khan N, Tran KA, Chevre R, Locher V, Richter M, Sun S, Sadeghi M, Pernet E, Herrero-Cervera A, Grant A, Saif A, Downey J, Kaufmann E, Khader SA, Joubert P, Barreiro LB, Yipp BG, Soehnlein O, Divangahi M.

PubMed ID: 39779870

Nargis Khan Lab

A forward genetic screen identifies potassium channel essentiality in SHH medulloblastoma maintenance

Journal Issue: Dev Cell. 2025 Jan 20:S1534-5807(25)00001-2.

Authors: Fan JJ, Erickson AW, Carrillo-Garcia J, Wang X, Skowron P, Wang X, Chen X, Shan G, Dou W, Bahrampour S, Xiong Y, Dong W, Abeysundara N, Francisco MA, Pusong RJ, Wang W, Li M, Ying E, Suárez RA, Farooq H, Holgado BL, Wu X, Daniels C, Dupuy AJ, Cadiñanos J, Bradley A, Bagchi A, Moriarity BS, Largaespada DA, Morrissy AS, Ramaswamy V, Mack SC, Garzia L, Dirks PB, Li X, Wanggou S, Egan S, Sun Y, Taylor MD, Huang X.

PubMed ID: 39862856

Xi Huang Lab

Journal Issue: Nat Commun. 2025 Jan 12;16(1):609.

Authors: Merrill SM, Konwar C, Fatima F, Dever K, MacIsaac JL, Letourneau N, Giesbrecht GF, Dewey D, England-Mason G, Lewis CR, Wang D, Teh AL, Meaney MJ, Gonzalez A, Noll JG, De Weerth C, Bush NR, O’Donnell KJ, Stewart SE, Kobor MS.

PubMed ID: 39800776

Michael Kobor Lab

Mitochondria- and ER-associated actin are required for mitochondrial fusion

Journal Issue: Nat Commun. 2025 Jan 7;16(1):451.

Authors: Gatti P, Schiavon C, Cicero J, Manor U, Germain M.

PubMed ID: 39774009

Marc Germain Lab