November 5, 2021

Canada in Science - November 5, 2021

Nat Biomed Eng. 2021 Oct;5(10):1157-1173.

Injectable and conductive cardiac patches repair infarcted myocardium in rats and minipigs

Wang L, Liu Y, Ye G, He Y, Li B, Guan Y, Gong B, Mequanint K, Xing MMQ, Qiu X

Sci Transl Med. 2021 Oct 13;13(615):eabj4011.

MR-guided focused ultrasound enhances delivery of trastuzumab to Her2-positive brain metastases

Meng Y, Reilly RM, Pezo RC, Trudeau M, Sahgal A, Singnurkar A, Perry J, Myrehaug S, Pople CB, Davidson B, Llinas M, Hyen C, Huang Y, Hamani C, Suppiah S, Hynynen K, Lipsman N

Cell Stem Cell. 2021 Oct 7;28(10):1838-1850.e10.

TFEB-mediated endolysosomal activity controls human hematopoietic stem cell fate

García-Prat L, Kaufmann KB, Schneiter F, Voisin V, Murison A, Chen J, Chan-Seng-Yue M, Gan OI, McLeod JL, Smith SA, Shoong MC, Parris D, Pan K, Zeng AGX, Krivdova G, Gupta K, Takayanagi SI, Wagenblast E, Wang W, Lupien M, Schroeder T, Xie SZ, Dick JE

PLoS Pathog. 2021 Oct 12;17(10):e1009965.

Efficacy of epetraborole against Mycobacterium abscessus is increased with norvaline

Sullivan JR, Lupien A, Kalthoff E, Hamela C, Taylor L, Munro KA, Schmeing TM, Kremer L, Behr MA.

Nat Commun. 2021 Oct 21;12(1):6137.

Orexin-A and endocannabinoids are involved in obesity-associated alteration of hippocampal neurogenesis, plasticity, and episodic memory in mice

Forte N, Boccella S, Tunisi L, Fernández-Rilo AC, Imperatore R, Iannotti FA, De Risi M, Iannotta M, Piscitelli F, Capasso R, De Girolamo P, De Leonibus E, Maione S, Di Marzo V, Cristino L.