{"id":31782,"date":"2025-07-29T12:22:03","date_gmt":"2025-07-29T16:22:03","guid":{"rendered":"https:\/\/www.bloomburton.com\/?p=31782"},"modified":"2025-07-29T12:22:03","modified_gmt":"2025-07-29T16:22:03","slug":"canada-in-science-june-2025","status":"publish","type":"post","link":"https:\/\/www.bloomburton.com\/wordpress\/canada-in-science-june-2025\/","title":{"rendered":"Canada in Science – June 2025"},"content":{"rendered":"\n
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<\/a>A disordered linker in the Polycomb protein Polyhomeotic tunes phase separation and oligomerization<\/a> <\/h4>\n<\/div>\n\n\n\n

Journal Issue<\/strong>: Mol Cell. 2025 Jun 5;85(11):2128-2146.e15.<\/p>\n\n\n\n

Authors:<\/strong> Gemeinhardt TM, Regy RM, Phan TM, Pal N, Sharma J, Senkovich O, Mendiola AJ, Ledterman HJ, Henrickson A, Lopes D, Kapoor U, Bihani A, Sihou D, Kim YC, Jeruzalmi D, Demeler B, Kim CA, Mittal J, Francis NJ.<\/p>\n\n\n\n

PubMed<\/strong> ID: <\/strong>40441156<\/p>\n\n\n\n

Nicole Francis Lab<\/a><\/p>\n\n\n\n

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A fungal-derived adjuvant amplifies the antitumoral potency of Bacillus Calmette-Gu\u00e9rin via reprogramming granulopoiesis<\/a><\/h4>\n<\/div>\n\n\n\n

Journal Issue<\/strong>: Immunity. 2025 Jun 19:S1074-7613(25)00247-X.<\/p>\n\n\n\n

Authors:<\/strong> Jurado LF, Daman AW, Li Z, Ross VMS, Nikolaou K, Tran KA, Loutochin O, McPherson VA, Pr\u00e9vel R, Taranc\u00f3n R, Couto K, Pernet E, Khan N, Cheong JG, Ramaiah R, Ketavarapu M, Kaufmann E, Glickman MS, Thanabalasuriar A, Josefowicz SZ, Divangahi M.<\/p>\n\n\n\n

PubMed<\/strong> ID: <\/strong>40555239<\/p>\n\n\n\n

Maziar Divangahi Lab<\/a> <\/p>\n\n\n\n

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Podocyte YAP and TAZ hyperactivation drives glomerular epithelial proliferative diseases in mice and humans<\/a><\/h4>\n<\/div>\n\n\n\n

Journal Issue<\/strong>: Science. 2025 May 1:eadk7633.<\/p>\n\n\n\n

Authors:<\/strong> He X, Ballestas ER, Zeng L, Zhang T, McEvoy CM, Misra PS, Ki V, Apostol A, Wong JS, Meliambro K, Ray J, De Cos M, Melica ME, Romagnani P, Feng Y, Krizova A, How I, Rosales IA, Colvin RB, He JC, Campbell KN, Yuen DA.<\/p>\n\n\n\n

PubMed<\/strong> ID: <\/strong>40560997<\/p>\n\n\n\n

Darren Yuen Lab<\/a><\/p>\n\n\n\n

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<\/span><\/a><\/a><\/a><\/a><\/a><\/a>Deep structure-function analysis of the endonuclease Mus81 with dominant mutational scanning<\/a><\/h4>\n<\/div>\n\n\n\n

Journal Issue<\/strong>: Proc Natl Acad Sci U S A. 2025 Jun 24;122(25):e2506043122.<\/p>\n\n\n\n

Authors:<\/strong> Oppedisano A, Bailey ML, Kumar A, O’Neil NJ, Stirling PC, Hieter P.<\/p>\n\n\n\n

PubMed<\/strong> ID: <\/strong>40531874<\/p>\n\n\n\n

Philip Hieter Lab<\/a><\/p>\n\n\n\n

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CDADC1 is a vertebrate-specific dCTP deaminase that metabolizes gemcitabine and decitabine to prevent cellular toxicity<\/a><\/h4>\n\n\n\n

Journal Issue<\/strong>: Proc Natl Acad Sci U S A. 2025 Jun 17;122(24):e2424409122.<\/p>\n<\/div>\n\n\n\n

Authors:<\/strong> Rodriguez MM, Chatterjee D, Guerry J, Patenaude AM, Cohen CCH, Bois T, Larouche A, Ferreira SR, Bertomeu T, Chatr-Aryamontri A, Zhang L, Mader S, Nislow C, St-Jean G, Guindon Y, Zahn A, Di Noia JM.<\/p>\n\n\n\n

PubMed<\/strong> ID: <\/strong>40504152<\/p>\n\n\n\n

Javier Di Noia Lab<\/a> <\/p>\n\n\n\n

<\/p>\n","protected":false},"excerpt":{"rendered":"

A disordered linker in the Polycomb protein Polyhomeotic tunes phase separation and oligomerization Journal Issue: Mol Cell. 2025 Jun 5;85(11):2128-2146.e15. Authors: Gemeinhardt TM, Regy RM, Phan TM, Pal N, Sharma J, Senkovich O, Mendiola AJ, Ledterman HJ, Henrickson A, Lopes D, Kapoor U, Bihani A, Sihou D, Kim YC, Jeruzalmi D, Demeler B, Kim CA, […]<\/p>\n","protected":false},"author":31,"featured_media":31792,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[122,126],"tags":[],"acf":{"sub_heading":"","background_image":false,"paragraph_after_image":"","date":"","slideshow_module":false,"type_of_background":"Image","image_background":false,"video_medium_background":"","video_mobile_background":"","has_dimmer":false,"dimmer_strength":"0.9"},"_links":{"self":[{"href":"https:\/\/www.bloomburton.com\/wordpress\/wp-json\/wp\/v2\/posts\/31782"}],"collection":[{"href":"https:\/\/www.bloomburton.com\/wordpress\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.bloomburton.com\/wordpress\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.bloomburton.com\/wordpress\/wp-json\/wp\/v2\/users\/31"}],"replies":[{"embeddable":true,"href":"https:\/\/www.bloomburton.com\/wordpress\/wp-json\/wp\/v2\/comments?post=31782"}],"version-history":[{"count":6,"href":"https:\/\/www.bloomburton.com\/wordpress\/wp-json\/wp\/v2\/posts\/31782\/revisions"}],"predecessor-version":[{"id":31791,"href":"https:\/\/www.bloomburton.com\/wordpress\/wp-json\/wp\/v2\/posts\/31782\/revisions\/31791"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.bloomburton.com\/wordpress\/wp-json\/wp\/v2\/media\/31792"}],"wp:attachment":[{"href":"https:\/\/www.bloomburton.com\/wordpress\/wp-json\/wp\/v2\/media?parent=31782"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.bloomburton.com\/wordpress\/wp-json\/wp\/v2\/categories?post=31782"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.bloomburton.com\/wordpress\/wp-json\/wp\/v2\/tags?post=31782"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}