{"id":31836,"date":"2025-09-24T13:11:25","date_gmt":"2025-09-24T17:11:25","guid":{"rendered":"https:\/\/www.bloomburton.com\/?p=31836"},"modified":"2025-09-24T13:39:35","modified_gmt":"2025-09-24T17:39:35","slug":"canada-in-science-august-2025","status":"publish","type":"post","link":"https:\/\/www.bloomburton.com\/wordpress\/canada-in-science-august-2025\/","title":{"rendered":"Canada in Science – August 2025"},"content":{"rendered":"\n
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<\/a>Ubiquitination of the histone variant mH2A1.2 prevents toxic RAD18 accumulation at a subset of genomic loci upon replication stress<\/a><\/a><\/h4>\n<\/div>\n\n\n\n

Journal Issue<\/strong>: Mol Cell. 2025 Aug 21;85(16):3023-3040.e10.<\/p>\n\n\n\n

Authors:<\/strong> Galloy M, Blondeau A, Vion \u00c9, Kim D, Bakker CA, Gaggioli V, Thomas M, Lavoie \u00c9G, Marois I, Delgado Monterroso AD, Masson JY, Taneja N, Miller KM, Mar\u00e9chal A, Fradet-Turcotte A.<\/p>\n\n\n\n

PubMed<\/strong> ID: <\/strong>40812313<\/p>\n\n\n\n

Amelie Fradet-Turcotte Lab<\/a><\/p>\n\n\n\n

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PALB2 and 53BP1 govern post-resection homologous recombination DNA repair<\/a><\/h4>\n<\/div>\n\n\n\n

Journal Issue<\/strong>: Mol Cell. 2025 Aug 7;85(15):2824-2838.e8.<\/p>\n\n\n\n

Authors:<\/strong> Wang Y, Coulombe Y, Yueh WT, Conway GD, Milano L, Glass DJ, Thomas M, Rodrigue A, Nacson J, Lu D, Bernhardy AJ, Betsch RG, Russo AI, Elfar GA, Cai KQ, Testa JR, Andrake M, Dunbrack R, Gupta GP, Xia B, Dray E, Masson JY, Johnson N.<\/p>\n\n\n\n

PubMed<\/strong> ID: <\/strong>40749686<\/p>\n\n\n\n

Jean-Yves Masson Lab<\/a><\/p>\n\n\n\n

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Amyloid-\u03b2-driven Alzheimer’s disease reshapes the colonic immune system in mice<\/a><\/h4>\n<\/div>\n\n\n\n

Journal Issue<\/strong>: Cell Rep. 2025 Aug 29:116109. doi: 10.1016\/j.celrep.2025.116109<\/p>\n\n\n\n

Authors:<\/strong> Makhijani P, Valentino TR, Manwaring-Mueller M, Emani R, Mu WC, Aguirre CG, Tan CR, Rane A, Wilson KA, Kifle A, Chen N, Du H, Wu F, Ng JHY, Ambrose BD, Ashok Kumaar PV, Khan S, Winer S, Wang C, Mortha A, Furman D, Schilling B, Ellerby LM, Rojas OL, Andersen JK, Winer DA.<\/p>\n\n\n\n

PubMed<\/strong> ID: <\/strong>40885186<\/p>\n\n\n\n

Olga Rojas Lab<\/a><\/p>\n\n\n\n

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<\/span><\/a><\/a><\/a><\/a><\/a><\/a>T cell receptor repertoire in cell-free DNA as a proxy for tumor infiltrates in patients treated with pembrolizumab<\/a><\/h4>\n<\/div>\n\n\n\n

Journal Issue<\/strong>: Cell Rep. 2025 Aug 26;44(9):116190.<\/p>\n\n\n\n

Authors:<\/strong> Soleimani S, Li X, Wang BX, Pedersen S, Bruce JP, Eagles J, Liu ZA, Bratman SV, Butler MO, Hansen AR, Bedard PL, Lheureux S, Spreafico A, Razak A, Siu LL, Ohashi PS, Pugh TJ.<\/p>\n\n\n\n

PubMed<\/strong> ID: <\/strong>40875293<\/p>\n\n\n\n

Trevor Pugh Lab<\/a><\/p>\n\n\n\n

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ITAF45 is a pervasive trans-acting factor for picornavirus Type II IRES elements<\/a><\/h4>\n\n\n\n

Journal Issue<\/strong>: Proc Natl Acad Sci U S A. 2025 Aug 19;122(33):e2506281122..<\/p>\n<\/div>\n\n\n\n

Authors:<\/strong> Bellucci MA, Amiri M, Berryman S, Moshari A, Owino CO, Luteijn RD, Tuthill TJ, Svitkin Y, Belsham GJ, van Kuppeveld FJM, Sonenberg N.<\/p>\n\n\n\n

PubMed<\/strong> ID:<\/strong> 40789037<\/p>\n\n\n\n

Nahum Soneneberg Lab<\/a><\/p>\n\n\n\n

<\/p>\n","protected":false},"excerpt":{"rendered":"

Ubiquitination of the histone variant mH2A1.2 prevents toxic RAD18 accumulation at a subset of genomic loci upon replication stress Journal Issue: Mol Cell. 2025 Aug 21;85(16):3023-3040.e10. Authors: Galloy M, Blondeau A, Vion \u00c9, Kim D, Bakker CA, Gaggioli V, Thomas M, Lavoie \u00c9G, Marois I, Delgado Monterroso AD, Masson JY, Taneja N, Miller KM, Mar\u00e9chal […]<\/p>\n","protected":false},"author":31,"featured_media":31841,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[122,126],"tags":[],"acf":{"sub_heading":"","background_image":false,"paragraph_after_image":"","date":"","slideshow_module":false,"type_of_background":"Image","image_background":false,"video_medium_background":"","video_mobile_background":"","has_dimmer":false,"dimmer_strength":"0.9"},"_links":{"self":[{"href":"https:\/\/www.bloomburton.com\/wordpress\/wp-json\/wp\/v2\/posts\/31836"}],"collection":[{"href":"https:\/\/www.bloomburton.com\/wordpress\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.bloomburton.com\/wordpress\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.bloomburton.com\/wordpress\/wp-json\/wp\/v2\/users\/31"}],"replies":[{"embeddable":true,"href":"https:\/\/www.bloomburton.com\/wordpress\/wp-json\/wp\/v2\/comments?post=31836"}],"version-history":[{"count":7,"href":"https:\/\/www.bloomburton.com\/wordpress\/wp-json\/wp\/v2\/posts\/31836\/revisions"}],"predecessor-version":[{"id":31845,"href":"https:\/\/www.bloomburton.com\/wordpress\/wp-json\/wp\/v2\/posts\/31836\/revisions\/31845"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.bloomburton.com\/wordpress\/wp-json\/wp\/v2\/media\/31841"}],"wp:attachment":[{"href":"https:\/\/www.bloomburton.com\/wordpress\/wp-json\/wp\/v2\/media?parent=31836"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.bloomburton.com\/wordpress\/wp-json\/wp\/v2\/categories?post=31836"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.bloomburton.com\/wordpress\/wp-json\/wp\/v2\/tags?post=31836"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}