{"id":32346,"date":"2026-03-03T14:29:26","date_gmt":"2026-03-03T18:29:26","guid":{"rendered":"https:\/\/www.bloomburton.com\/?p=32346"},"modified":"2026-03-03T14:29:27","modified_gmt":"2026-03-03T18:29:27","slug":"canada-in-science-january-2026","status":"publish","type":"post","link":"https:\/\/www.bloomburton.com\/wordpress\/canada-in-science-january-2026\/","title":{"rendered":"Canada in Science – January 2026"},"content":{"rendered":"\n
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Oxidized phosphatidylcholines deposition drives chronic neurodegeneration in a mouse model of progressive multiple sclerosis via IL-1\u03b2 signaling<\/a><\/h4>\n\n\n\n

Journal Issue: <\/strong>Nat Neurosci. 2026 Jan;29(1):67-80. doi: 10.1038\/s41593-025-02113-y.<\/p>\n\n\n\n

Authors: <\/strong>Yu R, Lozinski BM, Seifert A, Ta K, Zandee S, Kaushik DK, Park J, Klement W, Larouche S, Tsimikas S, Witztum JL, McGavern DB, Prat A, Dong Y.<\/p>\n\n\n\n

PubMed ID:<\/strong> 41326786<\/p>\n\n\n\n

Jeff Dong Lab<\/a><\/p>\n\n\n\n

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Patterns of hypermutation shape tumorigenesis and immunotherapy response in mismatch-repair-deficient glioma<\/a><\/h4>\n\n\n\n

Journal Issue:<\/strong> Nat Genet. 2026 Jan;58(1):132-142.<\/p>\n\n\n\n

Authors:<\/strong> Fernandez NR, Chang Y, Nunes NM, Dimayacyac JR, Levine A, Ringel A, Negm L, Ercan AB, Hess JM, Ahmad O, Lee C, Stengs L, Bianchi V, Edwards M, Doherty S, Chung J, Nobre L, Bennett J, Dodgshun AJ, Jones DTW, Pfister SM, Villani A, Malkin D, Ramaswamy V, Huang A, Bouffet E, Aronson M, Dirks PB, Shlien A, Getz G, Maruvka YE, Ertl-Wagner B, Hawkins C, Das A, Tabori U.<\/p>\n\n\n\n

PubMed ID:<\/strong> 41430480<\/p>\n\n\n\n

Uri Tabori Lab<\/a><\/p>\n\n\n\n

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Tunable differentiation of human CD4+<\/sup>\u00a0and CD8+<\/sup>\u00a0T cells from pluripotent stem cells<\/a><\/h4>\n\n\n\n

Journal Issue:<\/strong> Cell Stem Cell. 2026 Jan 8;33(1):73-90.e14.<\/p>\n\n\n\n

Authors:<\/strong> Jones RD, Salim K, Stankiewicz LN, Edgar JM, Leon L, Gillies JK, Murtaza A, Durland LJ, Raval D, Lau C, Taberna TPB, Hsu HH, Zimmerman C, Michaels YS, Rossi FMV, Levings MK, Zandstra PW.<\/p>\n\n\n\n

PubMed ID:<\/strong> 41512836<\/p>\n\n\n\n

Peter Zandstra Lab<\/a><\/p>\n\n\n\n

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Butyrolactol A enhances caspofungin efficacy via flippase inhibition in drug-resistant fungi<\/a><\/h4>\n\n\n\n

Journal Issue:<\/strong> Cell. 2026 Jan 22;189(2):620-639.e28.<\/p>\n\n\n\n

Authors:<\/strong> Chen X, Duan HD, Hoy MJ, Koteva K, Spitzer M, Guitor AK, Puumala E, Fiebig AA, Hu G, Yiu B, Chou S, Bian Z, Choi Y, Guo ABY, Wang W, Sun S, Robbins N, Averette AF, Cook MA, Truant R, MacNeil LT, Brown ED, Kronstad JW, Coombes BK, Cowen LE, Heitman J, Li H, Wright GD.<\/p>\n\n\n\n

PubMed ID:<\/strong> 41478284<\/p>\n\n\n\n

Gerard Wright Lab<\/a><\/p>\n\n\n\n

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Environmental enrichment and physical exercise prevent stress-induced social avoidance and blood-brain barrier alterations via Fgf2<\/a><\/h4>\n\n\n\n

Journal Issue:<\/strong> Nat Commun. 2026 Jan 16;17(1):1297.<\/p>\n\n\n\n

Authors:<\/strong> Paton SEJ, Solano JL, Cadoret A, Collignon A, Binder LB, Daigle B, Bevilacqua LM, Richer \u00c9, Coulombe-Rozon F, Dion-Albert L, Dudek KA; Signature Consortium; Lebel M, M\u00e9nard C.<\/p>\n\n\n\n

PubMed ID:<\/strong> 41545369<\/p>\n\n\n\n

Caroline Menard Lab<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

Oxidized phosphatidylcholines deposition drives chronic neurodegeneration in a mouse model of progressive multiple sclerosis via IL-1\u03b2 signaling Journal Issue: Nat Neurosci. 2026 Jan;29(1):67-80. doi: 10.1038\/s41593-025-02113-y. Authors: Yu R, Lozinski BM, Seifert A, Ta K, Zandee S, Kaushik DK, Park J, Klement W, Larouche S, Tsimikas S, Witztum JL, McGavern DB, Prat A, Dong Y. PubMed […]<\/p>\n","protected":false},"author":31,"featured_media":32360,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[122,126],"tags":[],"acf":{"sub_heading":"","background_image":false,"paragraph_after_image":"","date":"","slideshow_module":false,"type_of_background":"Image","image_background":false,"video_medium_background":"","video_mobile_background":"","has_dimmer":false,"dimmer_strength":"0.9"},"_links":{"self":[{"href":"https:\/\/www.bloomburton.com\/wordpress\/wp-json\/wp\/v2\/posts\/32346"}],"collection":[{"href":"https:\/\/www.bloomburton.com\/wordpress\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.bloomburton.com\/wordpress\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.bloomburton.com\/wordpress\/wp-json\/wp\/v2\/users\/31"}],"replies":[{"embeddable":true,"href":"https:\/\/www.bloomburton.com\/wordpress\/wp-json\/wp\/v2\/comments?post=32346"}],"version-history":[{"count":1,"href":"https:\/\/www.bloomburton.com\/wordpress\/wp-json\/wp\/v2\/posts\/32346\/revisions"}],"predecessor-version":[{"id":32353,"href":"https:\/\/www.bloomburton.com\/wordpress\/wp-json\/wp\/v2\/posts\/32346\/revisions\/32353"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.bloomburton.com\/wordpress\/wp-json\/wp\/v2\/media\/32360"}],"wp:attachment":[{"href":"https:\/\/www.bloomburton.com\/wordpress\/wp-json\/wp\/v2\/media?parent=32346"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.bloomburton.com\/wordpress\/wp-json\/wp\/v2\/categories?post=32346"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.bloomburton.com\/wordpress\/wp-json\/wp\/v2\/tags?post=32346"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}