January 12, 2026
Canada In Science - December 2025
A direct role for a mitochondrial targeting sequence in signalling stress
Journal Issue: Nature. 2025 Dec 10. doi: 10.1038/s41586-025-09834-x.
Authors: Yuan Z, Balzarini M, Volpe M, Goldstein M, Peng TS, Hui E, Fang NN, Albihlal WS, Hajimohammadi M, Wei K, Yip CK, van Werven FJ, Mayor T, Weidberg H.
PubMed ID: 41372412
Subsecond dopamine fluctuations do not specify the vigor of ongoing actions
Journal Issue: Nat Neurosci. 2025 Dec;28(12):2432-2438.
Authors: Liu H, Melani R, Maltese M, Taniguchi J, Sankaramanchi A, Zeng R, Martin JR, Tritsch NX.
PubMed ID: 41214177
Turncoat antibodies unmasked in a model of autoimmune demyelination: From biology to therapy
Journal Issue: Proc Natl Acad Sci U S A. 2025 Dec 23;122(51):e2424988122.
Authors: Taghipour-Mirakmahaleh R, Morin F, Zhang Y, Bourhoven L, Béland LC, Zhou Q, Jaworski J, Park A, Dominguez JM, Corbeil J, Flanagan EP, Marignier R, Larochelle C, Kerfoot SM, Vallières L.
PubMed ID: 41405856
Medial entorhinal VIP-expressing interneurons receive input from the thalamic anterior dorsal nucleus and are critical for spatial memory
Journal Issue: Proc Natl Acad Sci U S A. 2025 Dec 23;122(51):e2425024122.
Authors: Oulé M, Badrinarayanan S, Sundar-Maccagno R, Brandon MP.
PubMed ID: 41397139
Locus coeruleus microcircuitry processes periaqueductal gray inputs into distinct outputs for regulation of pain and anxiety
Journal Issue: Cell Rep. 2025 Dec 23;44(12):116699.
Authors: Harding EK, Zhang Z, Yu WL, Ferron L, van den Hoogen NJ, Trang T, Zamponi GW.
PubMed ID: 41391146
