Canada in Science - February 2026

SLAMF6 as a drug-targetable suppressor of T cell immunity against cancer

Journal Issue: Nature. 2026 Feb 11. doi: 10.1038/s41586-026-10106-5.

Authors: Li B, Zhong MC, Galindo CC, Dou J, Qian J, Tang Z, Davidson D, Veillette A.

PubMed ID: 41673151

Andre Veillette Lab

LUMI-lab: A foundation model-driven autonomous platform enabling discovery of ionizable lipid designs for mRNA delivery

Journal Issue: Cell. 2026 Feb 24:S0092-8674(26)00099-1.

Authors: Xu Y, Cui H, Pang K, Li G, Gong F, Dong S, Wang B, Li B.

PubMed ID: 41742414

Li Bowen Lab

A pan-cancer compendium of 1,294 plasma cell-free DNA methylomes and fragmentomes enabling multicancer detection

Journal Issue: Nat Cancer. 2026 Feb;7(2):384-398.

Authors: Zeng Y, Abelman DD, Singhawansa A, Cheng N, Fang Y, Main SC, Bell E, Ye W, Luo P, Wilson SL, Stutheit-Zhao EY, Wong D, Znassi N, Chen K, Mohanraj S, Sanz-Garcia E, Notta F, Ghanekar A, Awadalla P, Lok BH, Hoffman MM, Kim RH, Zadeh G, De Carvalho DD, Bratman SV, Lupien M, Pugh TJ, He HH.

PubMed ID: 41714824

Housheng Hansen He Lab

Oriented cell divisions induce basal progenitors and regulate neural expansion across tissues and species

Journal Issue: Sci Adv. 2026 Feb 6;12(6):eadz6827.

Authors: Boulan B, Lacomme M, Benadjal A, Krueger M, Currie K, La Torre A, Chédotal A, Cayouette M.

PubMed ID: 41637507

Michel Cayouette Lab

Viral mimicry acts as a tumor suppressor in colitis

Journal Issue: Nat Commun. 2026 Feb 4;17(1):1313.

Authors: Larsen F, Jeong W, Schep D, Good HJ, Shin AE, Zhang L, Derouet MF, Wang TC, Castellani CA, Shooshtari P, Asfaha S.

PubMed ID: 41639092

Samuel Asfaha Lab