May 19, 2026
Canada in Science - March & April 2026
A unified platform for nucleoside analog synthesis
Journal Issue: Science. 2026 Mar 5:eaed6880. doi: 10.1126/science.aed6880.
Authors: Anketell MJ, Fung E, Liu W, Shinde M, He CQ, Ng KWC, Silverman SM, Campeau LC, Pantophlet R, Britton R.
PubMed ID: 41785328
Remote monitoring of heart failure exacerbations using a smartwatch
Journal Issue: Nat Med. 2026 Mar;32(3):924-933. doi: 10.1038/s41591-026-04247-3.
Authors: Gao Y, Moayedi Y, Foroutan F, Verma B, Kim B, Luca E, Brum M, Brahmbhatt DH, Duhamel J, Simard A, McIntosh C, Ross HJ.
PubMed ID: 41862772
Glucosylceramide-induced ectosomes propagate pathogenic α-synuclein in Parkinson’s disease
Journal Issue: Nat Cell Biol. 2026 Mar;28(3):492-506. doi: 10.1038/s41556-026-01871-6.
Authors: Jacquemyn J, Marriott B, Chang J, Iftikhar E, Chik K, Lee NYJ, Rubio Atonal LF, Green C, Wong J, Acevedo-Morantes C, Chen CX, Nicouleau M, You Z, Deneault E, Abdian N, Durcan TM, Jackson J, Ioannou MS
PubMed ID: 41680444
Fetal developmental trajectories following maternal immune activation are shaped by sex chromosome-gonadal interactions
Journal Issue: Proc Natl Acad Sci U S A. 2026 Mar 24;123(12):e2531595123
Authors: Randell AM, Hanrahan J, Salia S, Burry TN, Fowler LF, Maekawa AS, Sled JG, Kaushik DK, Cahill L, Swift-Gallant A.
PubMed ID: 41849388
LINC01929 mediates breast cancer immunosuppression and is an immunotherapy target
Journal Issue: iScience. 2026 Mar 17;29(4):115381. doi: 10.1016/j.isci.2026.115381.
Authors: Venkatesh J, Wasson MD, Arun RP, Cahill HF, Walker OL, Dean CA, Fernando W, MacLean MR, McLean ME, Khan B, Kruth PS, Sultonova M, Nersesian S, Lee SN, Longjohn MN, Hughes CS, Belbin TJ, Gaston D, Paulo JA, Knapp GC, Bethune G, Gujar S, Boudreau JE, Murphy JP, Marcato P.
PubMed ID: 41993692
Engineering tough blood clots for rapid haemostasis and enhanced regeneration
Journal Issue: Nature. 2026 Apr 29. doi: 10.1038/s41586-026-10412-y.
Authors: Jiang S, Bao G, Yang Z, Wu J, Yang X, Kim JEJ, Jiang R, Zhan Y, Nottegar A, Liu Y, Gao ZH, Beckett A, Nijnik A, Long R, Kastrup C, Li J
PubMed ID: 42056507
The spatiotemporal dynamics of postnatal vascularization in the mouse brain
Journal Issue: Cell. 2026 Apr 14:S0092-8674(26)00280-1.
Authors: de Launoit E, Skriabine S, Doumazane E, Bizou M, Pommé R, Lienhard G, Rajot D, Mikhailenko A, Vieites-Prado A, Lannes M, Fabiano N, Mathé L, Cagnone G, Mouton L, Santin MD, Candelier S, Gaspar P, Rousseau CV, Dubrac A, Renier N.
PubMed ID: 41985458
A multiobjective AI model for LNP engineering enhances tissue-selective mRNA delivery
Journal Issue: Nat Biotechnol. 2026 Apr 28. doi: 10.1038/s41587-026-03109-0.
Authors: Zhou M, Xu Y, Li G, Chen J, Savguira M, Seto B, Gong F, Thomson T, Chen J, Lu RXZ, Dong S, Chen D, Eileen C, Wu S, Zheng G, Li B.
PubMed ID: 41512836
Human pluripotent stem cell-derived atrioventricular node-like pacemaker cells exhibit biological conduction bridge properties
Journal Issue: Cell Stem Cell. 2026 Apr 2;33(4):571-588.e13. doi: 10.1016/j.stem.2026.02.012
Authors: Lohbihler M, Lim AA, Massé S, Murareanu BM, Kwan M, Mourad O, Mastikhina O, Elbatarny M, Sarao R, Qiang B, Dhahri W, Chang ML, Xu ALY, Suthiwanich K, Chen M, Mazine A, Khattak S, Nunes SS, Nanthakumar K, Laflamme MA, Protze S.
PubMed ID: 41875893
Microbial metabolism of food allergens determines the severity of IgE-mediated anaphylaxis
Journal Issue: Cell Host Microbe. 2026 Apr 8;34(4):600-619.e9.
Authors: Sánchez-Martínez E, Rondeau LE, Garrido-Romero M, da Luz BB, Haas DA, Yuen G, Coppens D, Hall P, Dang R, Wang XY, Moreno-Serna L, López-Sanz C, Nuñez-Borque E, Garrido-Arandia M, Diaz-Perales A, Carrasco YR, Koenig JFE, Walker TD, Jordana M, Verdu EF, Bercik P, De Palma G, Surette MG, Ojeda P, Vega F, Blanco C, Zhang L, Bunyavanich S, Shreffler WG, Patil SU, Moreno FJ, Jiménez-Saiz R, Caminero A.
PubMed ID: 41780533
