Canada in Science - May 2026

Human haematopoietic stem cells remember inflammatory stress

Journal Issue: Nature. 2026 May 27. doi: 10.1038/s41586-026-10522-7.

Authors: Zeng AGX, Nagree MS, Jakobsen NA, Shah S, Varesi A, Kang JRW, Murison A, Cheong JG, Turkalj S, Zhang X, Radtke FA, Abera TA, Lim INX, Jin L, Araújo J, Aguilar-Navarro AG, Parris D, McLeod J, Kim H, Lee HS, Zhang L, Boulanger M, Bader E, Gbeha E, Parkhurst CN, Wagenblast E, Flores-Figueroa E, Wang B, Schwartz GW, Shultz LD, Nam AS, Grimes HL, Josefowicz SZ, Awadalla P, Vyas P, Dick JE, Xie SZ.

PubMed ID: 42203882

Stephanie Xie Lab

Transposable elements shape stemness in normal and leukemic hematopoiesis

Journal Issue: Nat Genet. 2026 May;58(5):1087-1099. doi: 10.1038/s41588-026-02585-z.

Authors: Grillo G, Nadorp B, Qamra A, Drylie B, Mitchell A, Arlidge C, Nand A, Takayama N, Murison A, Madani Tonekaboni SA, Kang KK, Arruda A, Wang JCY, Minden MD, Deniz Ö, Boutzen H, Dick JE, Lupien M.

PubMed ID: 42082719

Mathieu Lupien Lab

Microglia-dependent regulation of fear memory extinction

Journal Issue: Nat Neurosci. 2026 May 4. doi: 10.1038/s41593-026-02286-0.

Authors: Liu Y, Wo J, Kramer EE, Chen X, Park S, Huang S, Lin C, Josselyn SA, Frankland PW.

PubMed ID: 42082816

Josselyn-Frankland Lab

Mapping neuro-vascular unit communications reveals distinct angiogenic programs across developing mouse brain regions

Journal Issue: Nat Commun. 2026 May 22. doi: 10.1038/s41467-026-73373-w

Authors: Bizou M, Drapé E, Cagnone G, Howard JP, Irgolitsch F, Leclerc S, Chen MX, Boisseau B, Robillard I, Ruiz M, Lesage F, Joyal JS, Andelfinger G, Dubrac A.

PubMed ID: 42173924

Alexandre Dubrac Lab