November 24, 2025
Canada in Science - October 2025
Molecular subtypes of human skeletal muscle in cancer cachexia
Journal Issue: Nature. 2025 Oct;646(8086):973-982.
Authors: Bhatt BJ, Ghosh S, Mazurak V, Brun AQ, Bathe O, Baracos VE, Damaraju S
PubMed ID: 40931079
Augmenting AMPA receptor signaling after spinal cord injury increases ependymal-derived neural stem/progenitor cell migration and promotes functional recovery
Journal Issue: Nat Neurosci. 2025 Oct;28(10):2054-2066.
Authors: Hachem LD, Moradi Chameh H, Balbinot G, Mothe AJ, Pacis A, Geng Li RT, Valiante TA, Lu W, Tator CH, Fehlings MG.
PubMed ID: 40954308
Characterizing the physiology of circulatory arrest in humans
Journal Issue: Nat Med. 2025 Oct;31(10):3542-3552.
Authors: Bird JD, Hornby L, Hirsch-Reinshagen V, Allen CP, Isac G, Gooderham PA, Shemie SD, Dhanani S, Thiara S, Stukas S, Grey R, Foster DA, Maier LE, LeBlanc AE, Kanji HD, Morelli TF, Agbay AM, Wellington CL, Chahal D, Belanger EC, Ren H, Mattu PS, Su S, Hrazdil CT, Percy J, Sangha P, Plewes LV, Sweet DD, Romano KR, Vu EN, Chittock DR, Dhingra VK, Henderson WR, Garraway NR, Morad Hameed S, Finlayson GN, MacLeod DB, Gibbons TD, Ainslie PN, Hoiland RL, Griesdale DE, Ronco JJ, Sekhon MS.
PubMed ID: 41102468
MAPL regulates gasdermin-mediated release of mtDNA from lysosomes to drive pyroptotic cell death
Journal Issue: Nat Cell Biol. 2025 Oct;27(10):1708-1724.
Authors: Nguyen M, Collier JJ, Ignatenko O, Morin G, Goyon V, Janer A, Tiefensee Ribeiro C, Milnerwood AJ, Huang S, Desjardins M, McBride HM
PubMed ID: 41083601
Contextual regulation of T follicular helper cell expansion and differentiation into T regulatory type 1 cells by multiple transcription factors
Journal Issue: Cell Rep. 2025 Oct 28;44(10):116381.
Authors: Garnica J, Yamanouchi J, Thiessen S, Moro J, Canut E, Palou M, Mondal D, Serra P, Santamaria P.
PubMed ID: 41100252
