Canada in Science - December 2023

CD47 masks pro-phagocytic ligands in cis on tumor cells to suppress antitumor immunity

Journal Issue: Nat Immunol. 2023 Dec;24(12):2032-2041.

Authors: Tang Z, Zhong MC, Qian J, Galindo CC, Davidson D, Li J, Zhao Y, Hui E, Veillette A.

PubMed ID: 37945822

Andre Veillette Lab

Systematic analysis of alternative exon-dependent interactome remodeling reveals multitasking functions of gene regulatory factors

Journal Issue: Mol Cell. 2023 Dec 7;83(23):4222-4238.e10.

Authors: Roth JF, Braunschweig U, Wu M, Li JD, Lin ZY, Larsen B, Weatheritt RJ, Gingras AC, Blencowe BJ.

PubMed ID: 38065061

Benjamin Blencowe Lab

Fiber-deficient diets reprogram the microbiota

Journal Issue: Cell Host Microbe. 2023 Dec 13;31(12):1950-1951.

Authors: Fitzgerald BG, Sorbara MT.  

PubMed ID: 38096786

Matthew Sorbara Lab

EZH2 inhibition stimulates repetitive element expression and viral mimicry in resting splenic B cells

Journal Issue: EMBO J. 2023 Dec 11;42(24):e114462.

Authors: Kim SJ, Kiser PK, Asfaha S, DeKoter RP, Dick FA.

PubMed ID: 37934086

Frederick Dick Lab

Hypothalamic CRH neurons represent physiological memory of positive and negative experience

Journal Issue: Nat Commun. 2023 Dec 21;14(1):8522.

Authors: Füzesi T, Rasiah NP, Rosenegger DG, Rojas-Carvajal M, Chomiak T, Daviu N, Molina LA, Simone K, Sterley TL, Nicola W, Bains JS.

PubMed ID: 38129411

Jaideep Bains Lab