Canada in Science - June 2023

Cartilage-like protein hydrogels engineered via entanglement

Journal Issue: Nature. 2023 Jun;618(7966):740-747.

Authors: Fu L, Li L, Bian Q, Xue B, Jin J, Li J, Cao Y, Jiang Q, Li H.

PubMed ID: 37344650

Hongbin Li Lab

The mRNA translation initiation factor eIF4G1 controls mitochondrial oxidative phosphorylation, axonal morphogenesis, and memory

Journal Issue: Proc Natl Acad Sci U S A. 2023 Jun 20;120(25):e2300008120.

Authors: Kim SH, Choi JH, Marsal-García L, Amiri M, Yanagiya A, Sonenberg N.

PubMed ID: 37307456

Nahum Sonenberg Lab

Mechanism of mycobacterial ATP synthase inhibition by squaramides and second generation diarylquinolines

Journal Issue: EMBO J. 2023 Jun 28;e113687. doi: 10.15252/embj.2023113687.

Authors: Courbon GM, Palme PR, Mann L, Richter A, Imming P, Rubinstein JL.

PubMed ID: 37377118

John Rubinstein Lab

The contribution of inflammatory astrocytes to BBB impairments in a brain-chip model of Parkinson’s disease

Journal Issue: Nat Commun. 2023 Jun 20;14(1):3651. doi: 10.1038/s41467-023-39038-8.

Authors: de Rus Jacquet A, Alpaugh M, Denis HL, Tancredi JL, Boutin M, Decaestecker J, Beauparlant C, Herrmann L, Saint-Pierre M, Parent M, Droit A, Breton S, Cicchetti F.

PubMed ID: 37339976

Francesca Cicchetti Lab

Human papillomavirus integration transforms chromatin to drive oncogenesis

Journal Issue: Genome Biol. 2023 Jun 27;24(1):142. doi: 10.1186/s13059-023-02926-9.

Authors: Karimzadeh M, Arlidge C, Rostami A, Lupien M, Bratman SV, Hoffman MM.

PubMed ID: 37365652

Michael Hoffman Lab