March 8, 2021

Canada in Science - March 8, 2021

Welcome to your Canada in Science Review for March 8th, 2021!

Mol Cell. 2021 Feb 10;S1097-2765(21)00058-7. doi: 10.1016/j.molcel.2021.01.038.

DNA hypomethylating agents increase activation and cytolytic activity of CD8 + T cells

Nature. 2021 Feb;590(7846):480-485. doi: 10.1038/s41586-021-03221-y. Epub 2021 Feb 17.

Creatine kinase B controls futile creatine cycling in thermogenic fat

Nat Med. 2021 Feb 25. doi: 10.1038/s41591-021-01281-1. 

A Neanderthal OAS1 isoform protects individuals of European ancestry against COVID-19 susceptibility and severity

PLoS Med. 2021 Feb 25;18(2):e1003536. doi: 10.1371/journal.pmed.1003536.

Vitamin D levels and risk of type 1 diabetes: A Mendelian randomization study

PLoS Pathog. 2021 Feb 26;17(2):e1009295. doi: 10.1371/journal.ppat.1009295. 

SND1 promotes Th1/17 immunity against chlamydial lung infection through enhancing dendritic cell function