Canada in Science - May 2023

Deep learning-guided discovery of an antibiotic targeting Acinetobacter baumannii

Journal Issue: Nat Chem Biol. 2023 May 25. doi: 10.1038/s41589-023-01349-8..

Authors: Liu G, Catacutan DB, Rathod K, Swanson K, Jin W, Mohammed JC, Chiappino-Pepe A, Syed SA, Fragis M, Rachwalski K, Magolan J, Surette MG, Coombes BK, Jaakkola T, Barzilay R, Collins JJ, Stokes JM.

PubMed ID: 37231267

Jonathan Stokes Lab

Peroxisome biogenesis initiated by protein phase separation

Journal Issue: Nature. 2023 May;617(7961):608-615.

Authors: Sorin M, Ravindran R, Bacellar IOL, Castellanos-Girouard X, Wahba HM, Zhang Z, Omichinski JG, Kisley L, Michnick SW.

PubMed ID: 37165185

Stephen Michnick Lab

A shift in the mechanisms controlling hippocampal engram formation during brain maturation

Journal Issue: Science. 2023 May 5;380(6644):543-551.

Authors: Ramsaran AI, Wang Y, Golbabaei A, Aleshin S, de Snoo ML, Yeung BA, Rashid AJ, Awasthi A, Lau J, Tran LM, Ko SY, Abegg A, Duan LC, McKenzie C, Gallucci J, Ahmed M, Kaushik R, Dityatev A, Josselyn SA, Frankland PW.

PubMed ID: 37141366

Paul Frankland Lab

Imaging the subcellular viscoelastic properties of mouse oocytes

Journal Issue: Cell Host Microbe. 2023 May 10;31(5):695-711.

Authors: Flé G, Van Houten E, Rémillard-Labrosse G, FitzHarris G, Cloutier G.

PubMed ID: 37186851

Guy Cloutier Lab

macroH2A2 antagonizes epigenetic programs of stemness in glioblastoma

Journal Issue: Nat Commun. 2023 May 27;14(1):3062.

Authors: Nikolic A, Maule F, Bobyn A, Ellestad K, Paik S, Marhon SA, Mehdipour P, Lun X, Chen HM, Mallard C, Hay AJ, Johnston MJ, Gafuik CJ, Zemp FJ, Shen Y, Ninkovic N, Osz K, Labit E, Berger ND, Brownsey DK, Kelly JJ, Biernaskie J, Dirks PB, Derksen DJ, Jones SJM, Senger DL, Chan JA, Mahoney DJ, De Carvalho DD, Gallo M.

PubMed ID: 37244935

Marco Gallo Lab