October 9, 2020

Canada in Science - October 9, 2020

Welcome to your Canada in Science Review for October 9th, 2020!

Nature. 2020 Oct;586(7827):120-126. doi: 10.1038/s41586-020-2746-2. Epub 2020 Sep 23

Functional genomic landscape of cancer-intrinsic evasion of killing by T cells

EMBO J. 2020 Sep 7;e103864. doi: 10.15252/embj.2019103864. 

Fxr1 regulates sleep and synaptic homeostasis

Nat Commun. 2020 Sep 24;11(1):4822. doi: 10.1038/s41467-020-18649-5. 

Abiraterone acetate preferentially enriches for the gut commensal Akkermansia muciniphila in castrate-resistant prostate cancer patients

PLoS Genet. 2020 Sep 8;16(9):e1009008. doi: 10.1371/journal.pgen.1009008. eCollection 2020 Sep.

Male-biased aganglionic megacolon in the TashT mouse model of Hirschsprung disease involves upregulation of p53 protein activity and Ddx3y gene expression

J Biol Chem. 2020 Sep 25;jbc.RA120.015360. doi: 10.1074/jbc.RA120.015360. 

Development and validation of a high-throughput whole-cell assay to investigate Staphylococcus aureus adhesion to host ligands